The Stone Pony of biotech? It’s a nice idea, but one need not travel all the way down the Shore to find a fitting analogy to match the collaboration, ingenuity and creativity of the New Jersey music scene to what is rising at the New Jersey Innovation Hub.
How about the Court Tavern of biotech? From bars to basements, the Hub City has a strong history of incubating countless singers, songwriters and groups in the way Asbury Park provided Bruce Springsteen a space to find his sound. And New Brunswick itself emerged as a key player during an Oct. 6 ribbon-cutting ceremony celebrating the arrival of the NJ Innovation Hub at the Health + Science Exchange in New Brunswick.
The nitty gritty
Since launching at HELIX H-1 in July, the hub has already grown from 16 member companies to 21. Powered by Portal Innovations, the 30,000-square-foot space on the ninth floor at 20 French St. features more than 140 lab benches; office space; over $2 million in shared, specialized equipment; access to an onsite, 35,000-square-foot vivarium; and more.
During his opening remarks, delivered in the central Johnson & Johnson Exchange, Portal Innovations founder and CEO John Flavin highlighted three “obvious” reasons his company got involved.
Beyond the right environment and the state’s legacy in innovation – where that Bruce analogy came in – the final point rang clear: “New Brunswick is the future.”
Flavin described Portal’s model as gritty and “recognizing that you can build biotechnology companies anywhere, if you have the right ingredients.
“And those … have to be on one end, a very strong academic underpinning medical infrastructure, and on the other end, strong industry, large companies that are able to take the innovation and bring it all the way through the FDA and to patients.”
Other speakers joining Flavin on the stage Tuesday also drew attention to that foundation in New Brunswick, including Rutgers University President William Tate IV, representatives from RWJBarnabas Health along with Hackensack Meridian Health, and Johnson & Johnson Chairman and CEO Joaquin Duato.
Crafted capital
Portal Innovations employs a “crafted capital” strategy.
“We back the entrepreneur and help them mitigate risks so that those ideas become more investible by downstream partners as you go into series A and B and into the IPO into the clinic,” Flavin explained. “And that crafted capital also means this, it’s the community. It’s all the people and the knowledge in the marketplace and making it easier for people like me, as an entrepreneur, to test my idea in a familiar setting before I go out on the road and try to pitch that idea to the outside world.”
New Brunswick checks all the boxes to support and help such an ecosystem thrive.
Referencing the access and proximity to other major markets, from main roadways and the Northeast Corridor rail line, the state’s unique talent pool and the redevelopment activity taking place, Flavin said the New Jersey Innovation Hub powered by Portal will establish a central space to bring those pieces together.
Chris Paladino was one of several high-profile residents inducted into the New Jersey Hall of Fame in 2026. See more from this year’s ceremony, featuring Danny DeVito, SZA, Hackensack Meridian Health CEO Robert Garrett, and more!
“And really, we have one person that personifies that more than any other,” Flavin continued, preparing to welcome New Brunswick Development Corp. President Christopher Paladino.
“What we do is not a sprint, but it’s more like a marathon relay,” Paladino said on the stage.
DEVCO’s fingerprints are all over New Brunswick. There’s the HELIX complex, currently underway, for example. H-1 at 20 French St. will stand as part of a trio of towers. H-2 will serve as the new headquarters for Nokia Bell Labs, underscoring the innovation already drawn to town. Meanwhile, H-3 will bring 43 stories, featuring housing and more. There’s also the Jack & Sheryl Morris Cancer Center, which introduced New Jersey’s first freestanding hospital of its kind in 2025. And the New Brunswick Performing Arts Center and Rutgers Honor College, and much more.
“The promise of the HELIX of the New Jersey Innovation Hub began with a simple idea,” Paladino explained, “What we can accomplish together is greater than what we can accomplish alone.”
The new New Brunswick
A key collaborator, Cahill noted in his remarks, that “For decades, New Brunswick has worked to establish itself as a center for healthcare, education, research and economic development.”
And “Today we’re seeing yet another results of our partnerships.”
He noted how the project also underscores New Brunswick’s approach to economic development.
“For our city, projects like this are so much more than about the businesses that are here. They’re about building a stronger local economy, creating new career and job opportunities, ensuring that the growth taking place in New Brunswick continues to benefit our residents and future generations,” Cahill said.
The Middlesex County Seat boasts a population of more than 57,000, according to U.S. Census Bureau Data.
The information tallies the total revenue from the healthcare and social assistance sectors at $2.5 billion in New Brunswick. Total accommodation and food service sales was next closest, at $2.5 million.
“We have extraordinary universities, we have world class healthcare systems, we have the greatest concentration of pharmaceutical and life science companies everywhere,” Paladino noted in his remarks. “We have researchers, physicians, entrepreneurs, investors, and most importantly, an extraordinary important talent.
“What we needed was a place to bring them together.”
Hometown legacy
From within that new dedicated space to convene, speakers also highlighted the legacy this next step builds upon.
“Every morning, I go to work in the same place where Johnson & Johnson started in 1886,” Duato said during his remarks.
Throughout the company’s evolution, he noted J&J has never left New Jersey, adding, “This state has been central in our past, and it’s also central in our future.”
But relying on the infrastructure the state offers – that in-demand workforce, the institutions of higher education, manufacturing capability and entrepreneurial spirit – isn’t enough.
“If we want to continue in this leadership position, we have to renew our investment in science, in talent and in the next generation of innovators. That’s why this hub is so important. It’s more than a laboratory and office space: It’s a place where students, researchers, entrepreneurs, investors and established companies like us can work together to accelerate innovation.”
It’s having that access to the right investors, the right network – both emphasized by Portal’s operating model – that makes it possible to transform ideas and research into products and ideas that will reach the public at large.
BioNJ opens New Brunswick office at NJ Innovation Hub
BioNJ revealed it would join the Hub this past spring. Speaking July 14 in New Brunswick, President and CEO Debbie Hart described the new satellite office as a natural extension of the organization’s mission. Keep reading.
And scaling is central.
Tate highlighted public policy as the prop for that pillar.
“Today we consider the power of public policy,” he said. “This building, this hub, is a product of that policy.”
The Rutgers president celebrates his official one-year anniversary in the role this fall. During his term at Louisiana State University, Tate presided over a 50% increase in research expenditures.
Speaking Oct. 6, he referenced 2020’s New Jersey Economic Recovery Act, crediting the legislation with creating new mechanisms to invest in life sciences, technology, entrepreneurship and commercialization in the Garden State.
Addressing the room he said, “You answered the question, is Middlesex County the place to build a competitive advantage? Collectively, we responded yes; and here we stand,” Tate said. “Rutgers is prepared to ensure that competitive advantage is earned.”
Speaking on behalf of the administration, state Chief Operating Officer Kellie Doucette also noted NJIH “closes a critical gap.” She added the governor would have more to say in the coming weeks about how New Jersey will strengthen its innovation economy.
Heart and soul
Portal Innovations President Pat Flavin explained it was a trip to Manhattan that got the team to consider New Jersey and New Brunswick.
“There was just something missing. It was just something that I couldn’t really put my finger on … kind of the soul that’s needed in the area to drive success.”
Owing in part to Paladino’s persistence, Flavin told NJBIZ the pivot wasn’t a hard sell, because New Jersey’s reputation precedes it.
He cited Rutgers, DEVCO and Paladino’s enthusiasm as indicators the Innovation Hub would come to fruition. Plus, there’s the talent – the experienced talent.
“That’s one of the hardest parts of building a biotech company. Can you get access to talent that’s done it before?” New Jersey checks that box. And a lot of folks here don’t necessarily want to commute into New York – though the accessibility is a perk – each day.
All aboard
NJEDA CEO Evan Weiss also touched on the power of proximity.
“One thing I know that the other innovation centers I’ve been to, what they don’t have is the Northeast border right there,” he said of the New Brunswick train station. “Every single day, 750,000 people are going to be taking a train on the corridor looking at this and think about what’s going on, how to become part of this.”
And that buzz is the most important part. As Paladino put it, “perhaps the most exciting thing about today is that breath of beginning.
“Years from now, people may walk through these buildings or this campus, see companies, discoveries and technologies that none of us standing here today could possibly imagine, but that’s exactly the point. Our responsibility was not to predict every innovation that would happen here. Our responsibility was to create a place where innovation could happen.”